AJC experts say the conflict reshaped regional dynamics, reaffirmed U.S.- Israel ties, exposed Iran ’s isolation, and opened new possibilities for diplomacy, deterrence, and expanding the Abraham Accords. The Biden administration rallied to Israel’s side when Israel struck Iran last year in retaliation for Iranian backing for its enemies in its war against Hamas in Gaza and Hezbollah and for an intense barrage of Iranian missiles on Israel . A compilation of analyses on the military and nuclear impact of Israel’s initial strikes, Tehran’s response options, the Trump administration’s next steps, public reactions inside Iran , and more. Throughout this conflict, Israeli officials have talked openly about wanting to see regime change in Iran . Has said — now they say it's not on the table. After prevaricating about whether the United States would enter Israel’s war on Iran , President Donald Trump finally made a decision. Early Sunday, US warplanes and submarines struck three of. U.S.- Iran relations expert says Trump coordinated with Israel to strike Iran People look over damage to buildings following Israeli airstrikes on June 13, 2025 in Tehran, Iran . Israel’s large-scale attack on Iran ’s nuclear and military structures threatens to further escalate Mideast tensions while weakening Iran and its proxy network. Iran’s reaction likely will include both direct attacks on Israel and retaliation via its remaining proxy groups. However, the obedience of some of those proxies is in question given current circumstances.
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